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A circulating reservoir of pathogenic-like CD4(+) T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment

OBJECTIVES: Systemic immunological processes are profoundly shaped by the micro-environments where antigen recognition occurs. Identifying molecular signatures distinctive of such processes is pivotal to understand pathogenic immune responses and manipulate them for therapeutic purposes. Unfortunate...

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Detalles Bibliográficos
Autores principales:	Spreafico, Roberto, Rossetti, Maura, van Loosdregt, Jorg, Wallace, Carol A, Massa, Margherita, Magni-Manzoni, Silvia, Gattorno, Marco, Martini, Alberto, Lovell, Daniel J, Albani, Salvatore
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2016
Materias:	Basic and Translational Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752664/ https://www.ncbi.nlm.nih.gov/pubmed/25498120 http://dx.doi.org/10.1136/annrheumdis-2014-206226

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