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Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage

OBJECTIVE: To use a computational approach to investigate the cellular and extracellular matrix changes that occur with age in the knee joints of mice. METHODS: Knee joints from an inbred C57/BL1/6 (ICRFa) mouse colony were harvested at 3–30 months of age. Sections were stained with H&E, Safrani...

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Detalles Bibliográficos
Autores principales:	Hui, Wang, Young, David A, Rowan, Andrew D, Xu, Xin, Cawston, Tim E, Proctor, Carole J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2016
Materias:	Basic and Translational Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752670/ https://www.ncbi.nlm.nih.gov/pubmed/25475114 http://dx.doi.org/10.1136/annrheumdis-2014-206295

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