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The matching quality of experimental and control interventions in blinded pharmacological randomised clinical trials: a methodological systematic review
BACKGROUND: Blinding is a pivotal method to avoid bias in randomised clinical trials. In blinded drug trials, experimental and control interventions are often designed to be matched, i.e. to appear indistinguishable. It is unknown how often matching procedures are inadequate, so we decided to system...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752749/ https://www.ncbi.nlm.nih.gov/pubmed/26873063 http://dx.doi.org/10.1186/s12874-016-0111-9 |