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The matching quality of experimental and control interventions in blinded pharmacological randomised clinical trials: a methodological systematic review

BACKGROUND: Blinding is a pivotal method to avoid bias in randomised clinical trials. In blinded drug trials, experimental and control interventions are often designed to be matched, i.e. to appear indistinguishable. It is unknown how often matching procedures are inadequate, so we decided to system...

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Detalles Bibliográficos
Autores principales: Bello, Segun, Wei, Maoling, Hilden, Jørgen, Hróbjartsson, Asbjørn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752749/
https://www.ncbi.nlm.nih.gov/pubmed/26873063
http://dx.doi.org/10.1186/s12874-016-0111-9