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MiR-23b targets cyclin G1 and suppresses ovarian cancer tumorigenesis and progression
BACKGROUND: It has been proposed that cyclin G1 (CCNG1) participates in p53-dependent G(1)–S and G(2) checkpoints and might function as an oncogenic protein in the initiation and metastasis of ovarian carcinoma. MicroRNA 23b (miR-23b) is a critical regulatory factor in the progression of many cancer...
Autores principales: | Yan, Jing, Jiang, Jing-yi, Meng, Xiao-Na, Xiu, Yin-Ling, Zong, Zhi-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752753/ https://www.ncbi.nlm.nih.gov/pubmed/26872615 http://dx.doi.org/10.1186/s13046-016-0307-1 |
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