Cargando…
Misregulation of the proline rich homeodomain (PRH/HHEX) protein in cancer cells and its consequences for tumour growth and invasion
The proline rich homeodomain protein (PRH), also known as haematopoietically expressed homeobox (HHEX), is an essential transcription factor in embryonic development and in the adult. The PRH protein forms oligomeric complexes that bind to tandemly repeated PRH recognition sequences within or at a d...
Autores principales: | Gaston, Kevin, Tsitsilianos, Maria-Angela, Wadey, Kerry, Jayaraman, Padma-Sheela |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752775/ https://www.ncbi.nlm.nih.gov/pubmed/26877867 http://dx.doi.org/10.1186/s13578-016-0077-7 |
Ejemplares similares
-
The Proline Rich Homeodomain Protein PRH/Hhex Forms Stable Oligomers That Are Highly Resistant to Denaturation
por: Shukla, Anshuman, et al.
Publicado: (2012) -
Inhibition of Intimal Thickening By PRH (Proline-Rich Homeodomain) in Mice
por: Reolizo, Lien M., et al.
Publicado: (2023) -
Proline-Rich Homeodomain protein (PRH/HHEX) is a suppressor of breast tumour growth
por: Kershaw, R M, et al.
Publicado: (2017) -
Dasatinib inhibits leukaemic cell survival by decreasing PRH/Hhex phosphorylation resulting in increased repression of VEGF signalling genes
por: Noy, Peter, et al.
Publicado: (2012) -
Blood platelets stimulate cancer extravasation through TGFβ-mediated downregulation of PRH/HHEX
por: Marcolino, Eudmar, et al.
Publicado: (2020)