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Why it is crucial to analyze non clonal chromosome aberrations or NCCAs?

Current cytogenetics has largely focused its efforts on the identification of recurrent karyotypic alterations, also known as clonal chromosomal aberrations (CCAs). The rationale of doing so seems simple: recurrent genetic changes are relevant for diseases or specific physiological conditions, while...

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Detalles Bibliográficos
Autores principales: Heng, Henry H. Q., Regan, Sarah M., Liu, Guo, Ye, Christine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752783/
https://www.ncbi.nlm.nih.gov/pubmed/26877768
http://dx.doi.org/10.1186/s13039-016-0223-2

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