AP39, a Mitochondria-Targeted Hydrogen Sulfide Donor, Supports Cellular Bioenergetics and Protects against Alzheimer's Disease by Preserving Mitochondrial Function in APP/PS1 Mice and Neurons

Increasing evidence suggests that mitochondrial functions are altered in AD and play an important role in AD pathogenesis. It has been established that H(2)S homeostasis is balanced in AD. The emerging mitochondrial roles of H(2)S include antioxidation, antiapoptosis, and the modulation of cellular...

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Detalles Bibliográficos
Autores principales: Zhao, Feng-li, Fang, Fang, Qiao, Pei-feng, Yan, Ning, Gao, Dan, Yan, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753001/
https://www.ncbi.nlm.nih.gov/pubmed/27057285
http://dx.doi.org/10.1155/2016/8360738

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