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Impact of age on transcatheter aortic valve implantation outcomes: a comparison of patients aged ≤ 80 years versus patients > 80 years

OBJECTIVE: To investigate the procedural outcomes and the long-term survival of patients undergoing transcatheter aortic valve implantation (TAVI) and compare study results of patients ≤ 80 years and patients > 80 years old. METHODS: A total of 240 patients treated with TAVI were divided into two...

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Autores principales: van der Kley, Frank, van Rosendael, Philippe J, Katsanos, Spyridon, Kamperidis, Vasileios, Marsan, Nina A, Karalis, Ioannis, de Weger, Arend, Palmen, Meindert, Bax, Jeroen J, Schalij, Martin J, Delgado, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753009/
https://www.ncbi.nlm.nih.gov/pubmed/26918010
http://dx.doi.org/10.11909/j.issn.1671-5411.2016.01.004
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author van der Kley, Frank
van Rosendael, Philippe J
Katsanos, Spyridon
Kamperidis, Vasileios
Marsan, Nina A
Karalis, Ioannis
de Weger, Arend
Palmen, Meindert
Bax, Jeroen J
Schalij, Martin J
Delgado, Victoria
author_facet van der Kley, Frank
van Rosendael, Philippe J
Katsanos, Spyridon
Kamperidis, Vasileios
Marsan, Nina A
Karalis, Ioannis
de Weger, Arend
Palmen, Meindert
Bax, Jeroen J
Schalij, Martin J
Delgado, Victoria
author_sort van der Kley, Frank
collection PubMed
description OBJECTIVE: To investigate the procedural outcomes and the long-term survival of patients undergoing transcatheter aortic valve implantation (TAVI) and compare study results of patients ≤ 80 years and patients > 80 years old. METHODS: A total of 240 patients treated with TAVI were divided into two groups according to age ≤ 80 years (n = 105; 43.8%) and > 80 years (n = 135; 56.2%). The baseline characteristics and the procedural outcomes were compared between these two groups of patients. RESULTS: With the exception of peripheral artery disease and hypercholesterolemia, which were more frequently observed in the older age group, baseline characteristics were comparable between groups. Complication rates did not differ significantly between patients ≤ 80 years and patients > 80 years. There were no differences in 30-day mortality rates between patients aged ≤ 80 years and patients > 80 years old (9.5% vs. 7.4%, respectively; P = 0.557). After a median follow-up of 28 months (interquartile range: 16–42 months), 50 (47.6%) patients aged ≤ 80 years died compared to 57 (42%) deaths in the group of patients > 80 years old (P = 0.404). CONCLUSION: The results of the present single center study showed that age did not significantly impact the outcomes of TAVI.
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spelling pubmed-47530092016-02-25 Impact of age on transcatheter aortic valve implantation outcomes: a comparison of patients aged ≤ 80 years versus patients > 80 years van der Kley, Frank van Rosendael, Philippe J Katsanos, Spyridon Kamperidis, Vasileios Marsan, Nina A Karalis, Ioannis de Weger, Arend Palmen, Meindert Bax, Jeroen J Schalij, Martin J Delgado, Victoria J Geriatr Cardiol Research Article OBJECTIVE: To investigate the procedural outcomes and the long-term survival of patients undergoing transcatheter aortic valve implantation (TAVI) and compare study results of patients ≤ 80 years and patients > 80 years old. METHODS: A total of 240 patients treated with TAVI were divided into two groups according to age ≤ 80 years (n = 105; 43.8%) and > 80 years (n = 135; 56.2%). The baseline characteristics and the procedural outcomes were compared between these two groups of patients. RESULTS: With the exception of peripheral artery disease and hypercholesterolemia, which were more frequently observed in the older age group, baseline characteristics were comparable between groups. Complication rates did not differ significantly between patients ≤ 80 years and patients > 80 years. There were no differences in 30-day mortality rates between patients aged ≤ 80 years and patients > 80 years old (9.5% vs. 7.4%, respectively; P = 0.557). After a median follow-up of 28 months (interquartile range: 16–42 months), 50 (47.6%) patients aged ≤ 80 years died compared to 57 (42%) deaths in the group of patients > 80 years old (P = 0.404). CONCLUSION: The results of the present single center study showed that age did not significantly impact the outcomes of TAVI. Science Press 2016-01 /pmc/articles/PMC4753009/ /pubmed/26918010 http://dx.doi.org/10.11909/j.issn.1671-5411.2016.01.004 Text en Institute of Geriatric Cardiology http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission.
spellingShingle Research Article
van der Kley, Frank
van Rosendael, Philippe J
Katsanos, Spyridon
Kamperidis, Vasileios
Marsan, Nina A
Karalis, Ioannis
de Weger, Arend
Palmen, Meindert
Bax, Jeroen J
Schalij, Martin J
Delgado, Victoria
Impact of age on transcatheter aortic valve implantation outcomes: a comparison of patients aged ≤ 80 years versus patients > 80 years
title Impact of age on transcatheter aortic valve implantation outcomes: a comparison of patients aged ≤ 80 years versus patients > 80 years
title_full Impact of age on transcatheter aortic valve implantation outcomes: a comparison of patients aged ≤ 80 years versus patients > 80 years
title_fullStr Impact of age on transcatheter aortic valve implantation outcomes: a comparison of patients aged ≤ 80 years versus patients > 80 years
title_full_unstemmed Impact of age on transcatheter aortic valve implantation outcomes: a comparison of patients aged ≤ 80 years versus patients > 80 years
title_short Impact of age on transcatheter aortic valve implantation outcomes: a comparison of patients aged ≤ 80 years versus patients > 80 years
title_sort impact of age on transcatheter aortic valve implantation outcomes: a comparison of patients aged ≤ 80 years versus patients > 80 years
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753009/
https://www.ncbi.nlm.nih.gov/pubmed/26918010
http://dx.doi.org/10.11909/j.issn.1671-5411.2016.01.004
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