Cargando…

Determine the Dose Distribution Using Ultrasound Parameters in MAGIC-f Polymer Gels

In this study, using methacrylic and ascorbic acid in gelatin initiated by copper (MAGIC-f) polymer gel after megavoltage energy exposure, the sensitivity of the ultrasound velocity and attenuation coefficient dose-dependent parameters was evaluated. The MAGIC-f polymer gel was irradiated under 1.25...

Descripción completa

Detalles Bibliográficos
Autores principales: Masoumi, Hossein, Mokhtari-Dizaji, Manijhe, Arbabi, Azim, Bakhshandeh, Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753354/
https://www.ncbi.nlm.nih.gov/pubmed/26924952
http://dx.doi.org/10.1177/1559325815625647
_version_ 1782415849482616832
author Masoumi, Hossein
Mokhtari-Dizaji, Manijhe
Arbabi, Azim
Bakhshandeh, Mohsen
author_facet Masoumi, Hossein
Mokhtari-Dizaji, Manijhe
Arbabi, Azim
Bakhshandeh, Mohsen
author_sort Masoumi, Hossein
collection PubMed
description In this study, using methacrylic and ascorbic acid in gelatin initiated by copper (MAGIC-f) polymer gel after megavoltage energy exposure, the sensitivity of the ultrasound velocity and attenuation coefficient dose-dependent parameters was evaluated. The MAGIC-f polymer gel was irradiated under 1.25 MeV cobalt-60, ranging from 0 to 60 Gy in 2-Gy steps, and received dose uniformity and accuracy of ±2%. After calibration of the ultrasonic systems with a frequency of 500 kHz, the parameters of ultrasound velocity and attenuation coefficient of the irradiated gel samples were measured. According to the dose–response curve, the ability of ultrasonic parameters was evaluated in dose rate readings. Based on a 4-order polynomial curve, fitted on the dose–response parameters of ultrasound velocity and attenuation coefficient and observed at 24 hours after irradiation, ultrasonic parameters had more sensitivity. The sensitivity of the dose–velocity and dose-attenuation coefficient curves was observed as 50 m/s/Gy and 0.06 dB/MHz/Gy over the linear range of 4 to 44 Gy, respectively. The ultrasonic parameters at 5°C, 15°C, and 25°C on the gel dosimeter after 0 to 60 Gy irradiation showed that readings at 25°C have higher sensitivity compared to 15°C and 5°C. Maximum sensitivity time and temperature readings of the MAGIC-f ultrasonic parameters were concluded 24 hours after irradiation and at a temperature of 25°C.
format Online
Article
Text
id pubmed-4753354
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-47533542016-02-26 Determine the Dose Distribution Using Ultrasound Parameters in MAGIC-f Polymer Gels Masoumi, Hossein Mokhtari-Dizaji, Manijhe Arbabi, Azim Bakhshandeh, Mohsen Dose Response Original Articles In this study, using methacrylic and ascorbic acid in gelatin initiated by copper (MAGIC-f) polymer gel after megavoltage energy exposure, the sensitivity of the ultrasound velocity and attenuation coefficient dose-dependent parameters was evaluated. The MAGIC-f polymer gel was irradiated under 1.25 MeV cobalt-60, ranging from 0 to 60 Gy in 2-Gy steps, and received dose uniformity and accuracy of ±2%. After calibration of the ultrasonic systems with a frequency of 500 kHz, the parameters of ultrasound velocity and attenuation coefficient of the irradiated gel samples were measured. According to the dose–response curve, the ability of ultrasonic parameters was evaluated in dose rate readings. Based on a 4-order polynomial curve, fitted on the dose–response parameters of ultrasound velocity and attenuation coefficient and observed at 24 hours after irradiation, ultrasonic parameters had more sensitivity. The sensitivity of the dose–velocity and dose-attenuation coefficient curves was observed as 50 m/s/Gy and 0.06 dB/MHz/Gy over the linear range of 4 to 44 Gy, respectively. The ultrasonic parameters at 5°C, 15°C, and 25°C on the gel dosimeter after 0 to 60 Gy irradiation showed that readings at 25°C have higher sensitivity compared to 15°C and 5°C. Maximum sensitivity time and temperature readings of the MAGIC-f ultrasonic parameters were concluded 24 hours after irradiation and at a temperature of 25°C. SAGE Publications 2016-02-11 /pmc/articles/PMC4753354/ /pubmed/26924952 http://dx.doi.org/10.1177/1559325815625647 Text en © The Author(s) 2016 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Articles
Masoumi, Hossein
Mokhtari-Dizaji, Manijhe
Arbabi, Azim
Bakhshandeh, Mohsen
Determine the Dose Distribution Using Ultrasound Parameters in MAGIC-f Polymer Gels
title Determine the Dose Distribution Using Ultrasound Parameters in MAGIC-f Polymer Gels
title_full Determine the Dose Distribution Using Ultrasound Parameters in MAGIC-f Polymer Gels
title_fullStr Determine the Dose Distribution Using Ultrasound Parameters in MAGIC-f Polymer Gels
title_full_unstemmed Determine the Dose Distribution Using Ultrasound Parameters in MAGIC-f Polymer Gels
title_short Determine the Dose Distribution Using Ultrasound Parameters in MAGIC-f Polymer Gels
title_sort determine the dose distribution using ultrasound parameters in magic-f polymer gels
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753354/
https://www.ncbi.nlm.nih.gov/pubmed/26924952
http://dx.doi.org/10.1177/1559325815625647
work_keys_str_mv AT masoumihossein determinethedosedistributionusingultrasoundparametersinmagicfpolymergels
AT mokhtaridizajimanijhe determinethedosedistributionusingultrasoundparametersinmagicfpolymergels
AT arbabiazim determinethedosedistributionusingultrasoundparametersinmagicfpolymergels
AT bakhshandehmohsen determinethedosedistributionusingultrasoundparametersinmagicfpolymergels