Data on megakaryocytes in the bone marrow of mice exposed to formaldehyde

Previously, we reported that occupational exposure to formaldehyde (FA) exposure in factory workers reduced platelet counts, http://dx.doi.org/10.1158/1055-9965.EPI-09-0762[1], while exposure in mice increased platelet counts http://dx.doi.org/10.1371/journal.pone.0074974[2]. Bone marrow megakaryocy...

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Autores principales: Zhang, Yuchao, McHale, Cliona M., Liu, Xudong, Yang, Xu, Ding, Shumao, Zhang, Luoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753386/
https://www.ncbi.nlm.nih.gov/pubmed/26937474
http://dx.doi.org/10.1016/j.dib.2015.12.058
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author Zhang, Yuchao
McHale, Cliona M.
Liu, Xudong
Yang, Xu
Ding, Shumao
Zhang, Luoping
author_facet Zhang, Yuchao
McHale, Cliona M.
Liu, Xudong
Yang, Xu
Ding, Shumao
Zhang, Luoping
author_sort Zhang, Yuchao
collection PubMed
description Previously, we reported that occupational exposure to formaldehyde (FA) exposure in factory workers reduced platelet counts, http://dx.doi.org/10.1158/1055-9965.EPI-09-0762[1], while exposure in mice increased platelet counts http://dx.doi.org/10.1371/journal.pone.0074974[2]. Bone marrow megakaryocyte (MK) numbers were also increased in exposed mice, as determined qualitatively. The data presented here are from a quantitative evaluation of MK numbers in the bone marrow histopathological slides from the previous FA exposure experiments in mice. Bone marrow slides were prepared using a single 5 μm section of femur from 2 mice randomly selected from each exposure group (n=9) treated with 0, 0.5 and 3.0 mg/m(3) FA by nose-only inhalation. MKs were systemically counted and average MK frequency was calculated as the total MK per slide divided by the number of fields evaluated. Data are presented visually as microscopy views and graphically as MK frequency.
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spelling pubmed-47533862016-03-02 Data on megakaryocytes in the bone marrow of mice exposed to formaldehyde Zhang, Yuchao McHale, Cliona M. Liu, Xudong Yang, Xu Ding, Shumao Zhang, Luoping Data Brief Data Article Previously, we reported that occupational exposure to formaldehyde (FA) exposure in factory workers reduced platelet counts, http://dx.doi.org/10.1158/1055-9965.EPI-09-0762[1], while exposure in mice increased platelet counts http://dx.doi.org/10.1371/journal.pone.0074974[2]. Bone marrow megakaryocyte (MK) numbers were also increased in exposed mice, as determined qualitatively. The data presented here are from a quantitative evaluation of MK numbers in the bone marrow histopathological slides from the previous FA exposure experiments in mice. Bone marrow slides were prepared using a single 5 μm section of femur from 2 mice randomly selected from each exposure group (n=9) treated with 0, 0.5 and 3.0 mg/m(3) FA by nose-only inhalation. MKs were systemically counted and average MK frequency was calculated as the total MK per slide divided by the number of fields evaluated. Data are presented visually as microscopy views and graphically as MK frequency. Elsevier 2016-02-05 /pmc/articles/PMC4753386/ /pubmed/26937474 http://dx.doi.org/10.1016/j.dib.2015.12.058 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Zhang, Yuchao
McHale, Cliona M.
Liu, Xudong
Yang, Xu
Ding, Shumao
Zhang, Luoping
Data on megakaryocytes in the bone marrow of mice exposed to formaldehyde
title Data on megakaryocytes in the bone marrow of mice exposed to formaldehyde
title_full Data on megakaryocytes in the bone marrow of mice exposed to formaldehyde
title_fullStr Data on megakaryocytes in the bone marrow of mice exposed to formaldehyde
title_full_unstemmed Data on megakaryocytes in the bone marrow of mice exposed to formaldehyde
title_short Data on megakaryocytes in the bone marrow of mice exposed to formaldehyde
title_sort data on megakaryocytes in the bone marrow of mice exposed to formaldehyde
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753386/
https://www.ncbi.nlm.nih.gov/pubmed/26937474
http://dx.doi.org/10.1016/j.dib.2015.12.058
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