Cargando…

Macrophages programmed by apoptotic cells inhibit epithelial-mesenchymal transition in lung alveolar epithelial cells via PGE(2), PGD(2), and HGF

Apoptotic cell clearance results in the release of growth factors and the action of signaling molecules involved in tissue homeostasis maintenance. Here, we investigated whether and how macrophages programmed by apoptotic cells inhibit the TGF-β1-induced Epithelial-mesenchymal transition (EMT) proce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yoon, Young-So, Lee, Ye-Ji, Choi, Youn-Hee, Park, Young Mi, Kang, Jihee Lee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753481/ https://www.ncbi.nlm.nih.gov/pubmed/26875548 http://dx.doi.org/10.1038/srep20992

Ejemplares similares

Gas6 Prevents Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells via Production of PGE(2), PGD(2) and Their Receptors
por: Jung, Jihye, et al.
Publicado: (2019)

Interaction of Apoptotic Cells with Macrophages Upregulates COX-2/PGE(2) and HGF Expression via a Positive Feedback Loop
por: Byun, Ji Yeon, et al.
Publicado: (2014)

RhoA-Dependent HGF and c-Met Mediate Gas6-Induced Inhibition of Epithelial–Mesenchymal Transition, Migration, and Invasion of Lung Alveolar Epithelial Cells
por: Jung, Jihye, et al.
Publicado: (2019)

The Role of PGE(2) in Alveolar Epithelial and Lung Microvascular Endothelial Crosstalk
por: Bärnthaler, Thomas, et al.
Publicado: (2017)

Interaction of macrophages with apoptotic cells inhibits transdifferentiation and invasion of lung fibroblasts
por: Kim, Yong-Bae, et al.
Publicado: (2017)

The TAM-family receptor Mer mediates production of HGF through the RhoA-dependent pathway in response to apoptotic cells
por: Park, Hyun-Jung, et al.
Publicado: (2012)

Clearance of apoptotic cells by mesenchymal stem cells contributes to immunosuppression via PGE2
por: Zhang, Zhuoya, et al.
Publicado: (2019)

The anti-fibrotic effects of mesenchymal stem cells on irradiated lungs via stimulating endogenous secretion of HGF and PGE2
por: Dong, Li-Hua, et al.
Publicado: (2015)

PGD Synthase and PGD(2) in Immune Resposne
por: Joo, Myungsoo, et al.
Publicado: (2012)

Pteridines and cytokines induce apoptotic cell death in alveolar epithelial cells
por: Schobersberger, W, et al.
Publicado: (1997)

Biosynthetic Crossover of 5-Lipoxygenase and Cyclooxygenase-2 Yields 5-Hydroxy-PGE(2) and 5-Hydroxy-PGD(2)
por: Nakashima, Fumie, et al.
Publicado: (2021)

Efferocytosis of apoptotic alveolar epithelial cells is sufficient to initiate lung fibrosis
por: Kim, Kevin K., et al.
Publicado: (2018)

HGF/MET Regulated Epithelial-Mesenchymal Transitions And Metastasis By FOSL2 In Non-Small Cell Lung Cancer
por: Yin, Jun, et al.
Publicado: (2019)

Macrophage-expressed IFN-β Contributes to Apoptotic Alveolar Epithelial Cell Injury in Severe Influenza Virus Pneumonia
por: Högner, Katrin, et al.
Publicado: (2013)

Mechanism of Na-K-ATPase Inhibition by PGE2 in Intestinal Epithelial Cells
por: Nepal, Niraj, et al.
Publicado: (2021)

Alveolar macrophages and epithelial cells: The art of living together
por: Clements, Derek, et al.
Publicado: (2021)

The Role of Macrophages and Alveolar Epithelial Cells in the Development of ARDS
por: Tao, Huan, et al.
Publicado: (2022)

Prostaglandin D(2) (PGD(2)); PGD(2) receptor subtype DP1
Publicado: (2011)

Grape Seed Proanthocyanidins Inhibit Melanoma Cell Invasiveness by Reduction of PGE(2) Synthesis and Reversal of Epithelial-to-Mesenchymal Transition
por: Vaid, Mudit, et al.
Publicado: (2011)

Correction: Macrophage-expressed IFN-β Contributes to Apoptotic Alveolar Epithelial Cell Injury in Severe Influenza Virus Pneumonia
por: Högner, Katrin, et al.
Publicado: (2016)

PGE(2) accounts for bidirectional changes in alveolar macrophage self-renewal with aging and smoking
por: Penke, Loka R, et al.
Publicado: (2020)

Trichostatin A inhibits radiation-induced epithelial-to-mesenchymal transition in the alveolar epithelial cells
por: Nagarajan, Devipriya, et al.
Publicado: (2017)

PGD(2) and CRTH2 counteract Type 2 cytokine–elicited intestinal epithelial responses during helminth infection
por: Oyesola, Oyebola O., et al.
Publicado: (2021)

Alveolar macrophages rely on GM-CSF from alveolar epithelial type 2 cells before and after birth
por: Gschwend, Julia, et al.
Publicado: (2021)

Retraction: Grape Seed Proanthocyanidins Inhibit Melanoma Cell Invasiveness by Reduction of PGE(2) Synthesis and Reversal of Epithelial-to-Mesenchymal Transition
Publicado: (2018)

Apolipoprotein A1 Inhibits TGF-β1–Induced Epithelial-to-Mesenchymal Transition of Alveolar Epithelial Cells
por: Baek, Ae Rin, et al.
Publicado: (2016)

Growth and adherence of Staphylococcus aureus were enhanced through the PGE(2) produced by the activated COX-2/PGE(2) pathway of infected oral epithelial cells
por: Wang, Yuxia, et al.
Publicado: (2017)

Targeting of the SF/HGF receptor to the basolateral domain of polarized epithelial cells
Publicado: (1994)

Proteinase-activated receptor 4 stimulation-induced epithelial-mesenchymal transition in alveolar epithelial cells
por: Ando, Seijitsu, et al.
Publicado: (2007)

Andrographolide attenuates epithelial‐mesenchymal transition induced by TGF‐β1 in alveolar epithelial cells
por: Li, Jingpei, et al.
Publicado: (2020)

Green Tea Catechins Reduce Invasive Potential of Human Melanoma Cells by Targeting COX-2, PGE(2) Receptors and Epithelial-to-Mesenchymal Transition
por: Singh, Tripti, et al.
Publicado: (2011)

Simvastatin treatment boosts benefits of apoptotic cell infusion in murine lung fibrosis
por: Lee, Ye-JI, et al.
Publicado: (2017)

Alveolar Epithelial Type II Cells Activate Alveolar Macrophages and Mitigate P. Aeruginosa Infection
por: Kannan, Shibichakravarthy, et al.
Publicado: (2009)

Microvesicle-Mediated Communication Within the Alveolar Space: Mechanisms of Uptake by Epithelial Cells and Alveolar Macrophages
por: Soni, Sanooj, et al.
Publicado: (2022)

Alveolar epithelial cells undergo epithelial-mesenchymal transition in acute interstitial pneumonia: a case report
por: Li, Hongbo, et al.
Publicado: (2014)

IL-27 inhibits the TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells
por: Dong, Zhaoxing, et al.
Publicado: (2016)

ER Stress is Involved in Epithelial-To-Mesenchymal Transition of Alveolar Epithelial Cells Exposed to a Hypoxic Microenvironment
por: Delbrel, Eva, et al.
Publicado: (2019)

Regorafenib reverses HGF‐induced sorafenib resistance by inhibiting epithelial‐mesenchymal transition in hepatocellular carcinoma
por: Chen, Weibo, et al.
Publicado: (2019)

Retraction: Green Tea Catechins Reduce Invasive Potential of Human Melanoma Cells by Targeting COX-2, PGE(2) Receptors and Epithelial-to-Mesenchymal Transition
Publicado: (2018)

Mycobacterium tuberculosis expressing phospholipase C subverts PGE(2) synthesis and induces necrosis in alveolar macrophages
por: Assis, Patricia A, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_r11122acc9tnn405utmrv67ero