Plasma exchange in Immunoglobulin A nephropathy with thrombotic microangiopathy and acute cortical necrosis

A 25-year-old female presented with decreased urine output, deranged renal function, thrombocytopenia, and hemolytic anemia. Kidney biopsy was consistent with thrombotic microangiopathy with acute cortical necrosis and Immunoglobulin A nephropathy (IgAN). Hemolytic anemia, thrombocytopenia and urine...

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Autores principales: Doddi, P., Gowda, K., Ramachandran, R., Nada, R., Kumar, V., Rathi, M., Kohli, H. S., Gupta, K. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753741/
https://www.ncbi.nlm.nih.gov/pubmed/26937078
http://dx.doi.org/10.4103/0971-4065.163423
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author Doddi, P.
Gowda, K.
Ramachandran, R.
Nada, R.
Kumar, V.
Rathi, M.
Kohli, H. S.
Gupta, K. L.
author_facet Doddi, P.
Gowda, K.
Ramachandran, R.
Nada, R.
Kumar, V.
Rathi, M.
Kohli, H. S.
Gupta, K. L.
author_sort Doddi, P.
collection PubMed
description A 25-year-old female presented with decreased urine output, deranged renal function, thrombocytopenia, and hemolytic anemia. Kidney biopsy was consistent with thrombotic microangiopathy with acute cortical necrosis and Immunoglobulin A nephropathy (IgAN). Hemolytic anemia, thrombocytopenia and urine output improved after five sessions of plasma exchange. Renal function showed a delayed recovery and serum creatinine normalized by 3 months. This is first case of successful use of plasma exchange in hemolytic uremic syndrome with cortical necrosis associated with IgAN.
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spelling pubmed-47537412016-03-02 Plasma exchange in Immunoglobulin A nephropathy with thrombotic microangiopathy and acute cortical necrosis Doddi, P. Gowda, K. Ramachandran, R. Nada, R. Kumar, V. Rathi, M. Kohli, H. S. Gupta, K. L. Indian J Nephrol Case Report A 25-year-old female presented with decreased urine output, deranged renal function, thrombocytopenia, and hemolytic anemia. Kidney biopsy was consistent with thrombotic microangiopathy with acute cortical necrosis and Immunoglobulin A nephropathy (IgAN). Hemolytic anemia, thrombocytopenia and urine output improved after five sessions of plasma exchange. Renal function showed a delayed recovery and serum creatinine normalized by 3 months. This is first case of successful use of plasma exchange in hemolytic uremic syndrome with cortical necrosis associated with IgAN. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4753741/ /pubmed/26937078 http://dx.doi.org/10.4103/0971-4065.163423 Text en Copyright: © 2016 Indian Journal of Nephrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Doddi, P.
Gowda, K.
Ramachandran, R.
Nada, R.
Kumar, V.
Rathi, M.
Kohli, H. S.
Gupta, K. L.
Plasma exchange in Immunoglobulin A nephropathy with thrombotic microangiopathy and acute cortical necrosis
title Plasma exchange in Immunoglobulin A nephropathy with thrombotic microangiopathy and acute cortical necrosis
title_full Plasma exchange in Immunoglobulin A nephropathy with thrombotic microangiopathy and acute cortical necrosis
title_fullStr Plasma exchange in Immunoglobulin A nephropathy with thrombotic microangiopathy and acute cortical necrosis
title_full_unstemmed Plasma exchange in Immunoglobulin A nephropathy with thrombotic microangiopathy and acute cortical necrosis
title_short Plasma exchange in Immunoglobulin A nephropathy with thrombotic microangiopathy and acute cortical necrosis
title_sort plasma exchange in immunoglobulin a nephropathy with thrombotic microangiopathy and acute cortical necrosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753741/
https://www.ncbi.nlm.nih.gov/pubmed/26937078
http://dx.doi.org/10.4103/0971-4065.163423
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