Necrotizing enterocolitis: controversies and challenges

Necrotizing enterocolitis is a devastating intestinal disease that affects ~5% of preterm neonates. Despite advancements in neonatal care, mortality remains high (30–50%) and controversy still persists with regards to the most appropriate management of neonates with necrotizing enterocolitis. Herein...

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Detalles Bibliográficos
Autores principales: Zani, Augusto, Pierro, Agostino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753995/
https://www.ncbi.nlm.nih.gov/pubmed/26918125
http://dx.doi.org/10.12688/f1000research.6888.1
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author Zani, Augusto
Pierro, Agostino
author_facet Zani, Augusto
Pierro, Agostino
author_sort Zani, Augusto
collection PubMed
description Necrotizing enterocolitis is a devastating intestinal disease that affects ~5% of preterm neonates. Despite advancements in neonatal care, mortality remains high (30–50%) and controversy still persists with regards to the most appropriate management of neonates with necrotizing enterocolitis. Herein, we review some controversial aspects regarding the epidemiology, imaging, medical and surgical management of necrotizing enterocolitis and we describe new emerging strategies for prevention and treatment.
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spelling pubmed-47539952016-02-24 Necrotizing enterocolitis: controversies and challenges Zani, Augusto Pierro, Agostino F1000Res Review Necrotizing enterocolitis is a devastating intestinal disease that affects ~5% of preterm neonates. Despite advancements in neonatal care, mortality remains high (30–50%) and controversy still persists with regards to the most appropriate management of neonates with necrotizing enterocolitis. Herein, we review some controversial aspects regarding the epidemiology, imaging, medical and surgical management of necrotizing enterocolitis and we describe new emerging strategies for prevention and treatment. F1000Research 2015-11-30 /pmc/articles/PMC4753995/ /pubmed/26918125 http://dx.doi.org/10.12688/f1000research.6888.1 Text en Copyright: © 2015 Zani A and Pierro A http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Zani, Augusto
Pierro, Agostino
Necrotizing enterocolitis: controversies and challenges
title Necrotizing enterocolitis: controversies and challenges
title_full Necrotizing enterocolitis: controversies and challenges
title_fullStr Necrotizing enterocolitis: controversies and challenges
title_full_unstemmed Necrotizing enterocolitis: controversies and challenges
title_short Necrotizing enterocolitis: controversies and challenges
title_sort necrotizing enterocolitis: controversies and challenges
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753995/
https://www.ncbi.nlm.nih.gov/pubmed/26918125
http://dx.doi.org/10.12688/f1000research.6888.1
work_keys_str_mv AT zaniaugusto necrotizingenterocolitiscontroversiesandchallenges
AT pierroagostino necrotizingenterocolitiscontroversiesandchallenges

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