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Advances in understanding and managing atopic dermatitis
Atopic dermatitis is a chronic, pruritic skin disease characterized by an improperly functioning skin barrier and immune dysregulation. We review proposed atopic dermatitis pathomechanisms, emphasizing how these impact current perspectives on natural history, role of allergic sensitization, and futu...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753999/ https://www.ncbi.nlm.nih.gov/pubmed/26918129 http://dx.doi.org/10.12688/f1000research.6972.1 |
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author | Barton, Michael Sidbury, Robert |
author_facet | Barton, Michael Sidbury, Robert |
author_sort | Barton, Michael |
collection | PubMed |
description | Atopic dermatitis is a chronic, pruritic skin disease characterized by an improperly functioning skin barrier and immune dysregulation. We review proposed atopic dermatitis pathomechanisms, emphasizing how these impact current perspectives on natural history, role of allergic sensitization, and future therapeutic targets. |
format | Online Article Text |
id | pubmed-4753999 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | F1000Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-47539992016-02-24 Advances in understanding and managing atopic dermatitis Barton, Michael Sidbury, Robert F1000Res Review Atopic dermatitis is a chronic, pruritic skin disease characterized by an improperly functioning skin barrier and immune dysregulation. We review proposed atopic dermatitis pathomechanisms, emphasizing how these impact current perspectives on natural history, role of allergic sensitization, and future therapeutic targets. F1000Research 2015-11-19 /pmc/articles/PMC4753999/ /pubmed/26918129 http://dx.doi.org/10.12688/f1000research.6972.1 Text en Copyright: © 2015 Barton M and Sidbury R http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Barton, Michael Sidbury, Robert Advances in understanding and managing atopic dermatitis |
title | Advances in understanding and managing atopic dermatitis |
title_full | Advances in understanding and managing atopic dermatitis |
title_fullStr | Advances in understanding and managing atopic dermatitis |
title_full_unstemmed | Advances in understanding and managing atopic dermatitis |
title_short | Advances in understanding and managing atopic dermatitis |
title_sort | advances in understanding and managing atopic dermatitis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753999/ https://www.ncbi.nlm.nih.gov/pubmed/26918129 http://dx.doi.org/10.12688/f1000research.6972.1 |
work_keys_str_mv | AT bartonmichael advancesinunderstandingandmanagingatopicdermatitis AT sidburyrobert advancesinunderstandingandmanagingatopicdermatitis |