Exome arrays capture polygenic rare variant contributions to schizophrenia

Schizophrenia is a highly heritable disorder. Genome-wide association studies based largely on common alleles have identified over 100 schizophrenia risk loci, but it is also evident from studies of copy number variants (CNVs) and from exome-sequencing studies that rare alleles are also involved. Fu...

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Detalles Bibliográficos
Autores principales: Richards, A. L., Leonenko, G., Walters, J. T., Kavanagh, D. H., Rees, E. G., Evans, A., Chambert, K. D., Moran, J. L., Goldstein, J., Neale, B. M., McCarroll, S. A., Pocklington, A. J., Holmans, P. A., Owen, M. J., O'Donovan, M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Association Studies Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754044/
https://www.ncbi.nlm.nih.gov/pubmed/26740555
http://dx.doi.org/10.1093/hmg/ddv620

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