Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics

Induced pluripotent stem cell (iPSC)-derived cortical neurons potentially present a powerful new model to understand corticogenesis and neurological disease. Previous work has established that differentiation protocols can produce cortical neurons, but little has been done to characterize these at c...

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Detalles Bibliográficos
Autores principales: Handel, Adam E., Chintawar, Satyan, Lalic, Tatjana, Whiteley, Emma, Vowles, Jane, Giustacchini, Alice, Argoud, Karene, Sopp, Paul, Nakanishi, Mahito, Bowden, Rory, Cowley, Sally, Newey, Sarah, Akerman, Colin, Ponting, Chris P., Cader, M. Zameel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754051/
https://www.ncbi.nlm.nih.gov/pubmed/26740550
http://dx.doi.org/10.1093/hmg/ddv637

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