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Loss of UBE3A from TH-expressing neurons suppresses GABA co-release and enhances VTA-NAc optical self-stimulation

Motivated reward-seeking behaviours are governed by dopaminergic ventral tegmental area projections to the nucleus accumbens. In addition to dopamine, these mesoaccumbal terminals co-release other neurotransmitters including glutamate and GABA, whose roles in regulating motivated behaviours are curr...

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Detalles Bibliográficos
Autores principales:	Berrios, Janet, Stamatakis, Alice M., Kantak, Pranish A., McElligott, Zoe A., Judson, Matthew C., Aita, Megumi, Rougie, Marie, Stuber, Garret D., Philpot, Benjamin D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754338/ https://www.ncbi.nlm.nih.gov/pubmed/26869263 http://dx.doi.org/10.1038/ncomms10702

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