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The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis

Metastasis is a critical event affecting breast cancer patient survival. To identify molecules contributing to the metastatic process, we analysed The Cancer Genome Atlas (TCGA) breast cancer data and identified 41 genes whose expression is inversely correlated with survival. Here we show that GABA(...

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Detalles Bibliográficos
Autores principales: Gumireddy, Kiranmai, Li, Anping, Kossenkov, Andrew V., Sakurai, Masayuki, Yan, Jinchun, Li, Yan, Xu, Hua, Wang, Jian, Zhang, Paul J., Zhang, Lin, Showe, Louise C., Nishikura, Kazuko, Huang, Qihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754346/
https://www.ncbi.nlm.nih.gov/pubmed/26869349
http://dx.doi.org/10.1038/ncomms10715