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Deficiency of cyclase-associated protein 2 promotes arrhythmias associated with connexin43 maldistribution and fibrosis

INTRODUCTION: Cyclase-associated protein 2 (CAP2) plays a major role in regulating the actin cytoskeleton. Since inactivation of CAP2 in a mouse model by a gene trap approach (Cap2(gt/gt)) results in cardiomyopathy and increased mortality, we hypothesized that CAP2 has a major impact on arrhythmias...

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Detalles Bibliográficos
Autores principales:	Stöckigt, Florian, Peche, Vivek Shahaji, Linhart, Markus, Nickenig, Georg, Noegel, Angelika Anna, Schrickel, Jan Wilko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Termedia Publishing House 2016
Materias:	Experimental Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754362/ https://www.ncbi.nlm.nih.gov/pubmed/26925136 http://dx.doi.org/10.5114/aoms.2015.54146

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