Joint Degradation in a Monkey Model of Collagen-Induced Arthritis: Role of Cathepsin K Based on Biochemical Markers and Histological Evaluation

The role of cathepsin K in joint degradation in a model of collagen-induced arthritis (CIA) in cynomolgus monkey was examined using biochemical markers and histology. Joint swelling, urinary C-telopeptide of type II collagen (CTX-II), deoxypyridinoline (DPD), and N- and C-telopeptides of type I coll...

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Detalles Bibliográficos
Autores principales: Tanaka, Makoto, Yamada, Hiroyuki, Nishikawa, Satoshi, Mori, Hiroshi, Ochi, Yasuo, Horai, Naoto, Li, Minqi, Amizuka, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754492/
https://www.ncbi.nlm.nih.gov/pubmed/26949397
http://dx.doi.org/10.1155/2016/8938916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754492/
https://www.ncbi.nlm.nih.gov/pubmed/26949397
http://dx.doi.org/10.1155/2016/8938916

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