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Joint Degradation in a Monkey Model of Collagen-Induced Arthritis: Role of Cathepsin K Based on Biochemical Markers and Histological Evaluation

The role of cathepsin K in joint degradation in a model of collagen-induced arthritis (CIA) in cynomolgus monkey was examined using biochemical markers and histology. Joint swelling, urinary C-telopeptide of type II collagen (CTX-II), deoxypyridinoline (DPD), and N- and C-telopeptides of type I coll...

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Detalles Bibliográficos
Autores principales:	Tanaka, Makoto, Yamada, Hiroyuki, Nishikawa, Satoshi, Mori, Hiroshi, Ochi, Yasuo, Horai, Naoto, Li, Minqi, Amizuka, Norio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754492/ https://www.ncbi.nlm.nih.gov/pubmed/26949397 http://dx.doi.org/10.1155/2016/8938916

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