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Cell contractility arising from topography and shear flow determines human mesenchymal stem cell fate

Extracellular matrix (ECM) of the human Mesenchymal Stem Cells (MSCs) influences intracellular tension and is known to regulate stem cell fate. However, little is known about the physiological conditions in the bone marrow, where external forces such as fluid shear stress, apart from the physical ch...

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Detalles Bibliográficos
Autores principales: Sonam, Surabhi, Sathe, Sharvari R., Yim, Evelyn K.F., Sheetz, Michael P., Lim, Chwee Teck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754642/
https://www.ncbi.nlm.nih.gov/pubmed/26879739
http://dx.doi.org/10.1038/srep20415