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Identification of a prostaglandin D(2) metabolite as a neuritogenesis enhancer targeting the TRPV1 ion channel

Mast cells play important roles in allergic inflammation by secreting various mediators. In the present study, based on the finding that the medium conditioned by activated RBL-2H3 mast cells enhanced the nerve growth factor (NGF)-induced neuritogenesis of PC12 cells, we attempted to isolate an acti...

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Detalles Bibliográficos
Autores principales: Shibata, Takahiro, Takahashi, Katsuhiro, Matsubara, Yui, Inuzuka, Emi, Nakashima, Fumie, Takahashi, Nobuaki, Kozai, Daisuke, Mori, Yasuo, Uchida, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754695/
https://www.ncbi.nlm.nih.gov/pubmed/26879669
http://dx.doi.org/10.1038/srep21261