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Identification of a prostaglandin D(2) metabolite as a neuritogenesis enhancer targeting the TRPV1 ion channel
Mast cells play important roles in allergic inflammation by secreting various mediators. In the present study, based on the finding that the medium conditioned by activated RBL-2H3 mast cells enhanced the nerve growth factor (NGF)-induced neuritogenesis of PC12 cells, we attempted to isolate an acti...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754695/ https://www.ncbi.nlm.nih.gov/pubmed/26879669 http://dx.doi.org/10.1038/srep21261 |