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Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models
Different neurodegenerative diseases are caused by aberrant elongation of repeated glutamine sequences normally found in particular human proteins. Although the proteins involved are ubiquitously distributed in human tissues, toxicity targets only defined neuronal populations. Changes caused by an e...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754714/ https://www.ncbi.nlm.nih.gov/pubmed/26880203 http://dx.doi.org/10.1083/jcb.201506025 |