Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models

Different neurodegenerative diseases are caused by aberrant elongation of repeated glutamine sequences normally found in particular human proteins. Although the proteins involved are ubiquitously distributed in human tissues, toxicity targets only defined neuronal populations. Changes caused by an e...

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Detalles Bibliográficos
Autores principales: Matos, Carlos A., Nóbrega, Clévio, Louros, Susana R., Almeida, Bruno, Ferreiro, Elisabete, Valero, Jorge, Pereira de Almeida, Luís, Macedo-Ribeiro, Sandra, Carvalho, Ana Luísa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754714/
https://www.ncbi.nlm.nih.gov/pubmed/26880203
http://dx.doi.org/10.1083/jcb.201506025

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