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Breaking down to build up: Neuroligin’s C-terminal domain strengthens the synapse
The mechanisms by which neuroligin adhesion molecules modulate synaptic plasticity remain unclear. In this issue, Liu et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201509023) demonstrate that neuroligin 1 promotes actin assembly associated with synaptic strengthening independent of adhes...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754722/ https://www.ncbi.nlm.nih.gov/pubmed/26880198 http://dx.doi.org/10.1083/jcb.201601081 |
| Sumario: | The mechanisms by which neuroligin adhesion molecules modulate synaptic plasticity remain unclear. In this issue, Liu et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201509023) demonstrate that neuroligin 1 promotes actin assembly associated with synaptic strengthening independent of adhesion, suggesting additional ways for neuroligins to contribute to neuronal development and disease pathology. |
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