Breaking down to build up: Neuroligin’s C-terminal domain strengthens the synapse

The mechanisms by which neuroligin adhesion molecules modulate synaptic plasticity remain unclear. In this issue, Liu et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201509023) demonstrate that neuroligin 1 promotes actin assembly associated with synaptic strengthening independent of adhes...

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Autor principal: Newell-Litwa, Karen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754722/
https://www.ncbi.nlm.nih.gov/pubmed/26880198
http://dx.doi.org/10.1083/jcb.201601081
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author Newell-Litwa, Karen A.
author_facet Newell-Litwa, Karen A.
author_sort Newell-Litwa, Karen A.
collection PubMed
description The mechanisms by which neuroligin adhesion molecules modulate synaptic plasticity remain unclear. In this issue, Liu et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201509023) demonstrate that neuroligin 1 promotes actin assembly associated with synaptic strengthening independent of adhesion, suggesting additional ways for neuroligins to contribute to neuronal development and disease pathology.
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spelling pubmed-47547222016-08-15 Breaking down to build up: Neuroligin’s C-terminal domain strengthens the synapse Newell-Litwa, Karen A. J Cell Biol Reviews The mechanisms by which neuroligin adhesion molecules modulate synaptic plasticity remain unclear. In this issue, Liu et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201509023) demonstrate that neuroligin 1 promotes actin assembly associated with synaptic strengthening independent of adhesion, suggesting additional ways for neuroligins to contribute to neuronal development and disease pathology. The Rockefeller University Press 2016-02-15 /pmc/articles/PMC4754722/ /pubmed/26880198 http://dx.doi.org/10.1083/jcb.201601081 Text en © 2016 Newell-Litwa This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Reviews
Newell-Litwa, Karen A.
Breaking down to build up: Neuroligin’s C-terminal domain strengthens the synapse
title Breaking down to build up: Neuroligin’s C-terminal domain strengthens the synapse
title_full Breaking down to build up: Neuroligin’s C-terminal domain strengthens the synapse
title_fullStr Breaking down to build up: Neuroligin’s C-terminal domain strengthens the synapse
title_full_unstemmed Breaking down to build up: Neuroligin’s C-terminal domain strengthens the synapse
title_short Breaking down to build up: Neuroligin’s C-terminal domain strengthens the synapse
title_sort breaking down to build up: neuroligin’s c-terminal domain strengthens the synapse
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754722/
https://www.ncbi.nlm.nih.gov/pubmed/26880198
http://dx.doi.org/10.1083/jcb.201601081
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