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Intranasal Insulin Prevents Anesthesia-Induced Spatial Learning and Memory Deficit in Mice

Elderly individuals are at increased risk of cognitive decline after anesthesia. General anesthesia is believed to be a risk factor for Alzheimer’s disease (AD). At present, there is no treatment that can prevent anesthesia-induced postoperative cognitive dysfunction. Here, we treated mice with dail...

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Detalles Bibliográficos
Autores principales: Zhang, Yongli, Dai, Chun-ling, Chen, Yanxing, Iqbal, Khalid, Liu, Fei, Gong, Cheng-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754754/
https://www.ncbi.nlm.nih.gov/pubmed/26879001
http://dx.doi.org/10.1038/srep21186