Transcriptional activation of follistatin by Nrf2 protects pulmonary epithelial cells against silica nanoparticle-induced oxidative stress

Silica nanoparticles (SiO(2) NPs) cause oxidative stress in respiratory system. Meanwhile, human cells launch adaptive responses to overcome SiO(2) NP toxicity. However, besides a few examples, the regulation of SiO(2) NP-responsive proteins and their functions in SiO(2) NP response remain largely u...

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Detalles Bibliográficos
Autores principales: Lin, Chen, Zhao, Xinyuan, Sun, Desen, Zhang, Lingda, Fang, Wenpan, Zhu, Tingjia, Wang, Qiang, Liu, Botao, Wei, Saisai, Chen, Guangdi, Xu, Zhengping, Gao, Xiangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754796/
https://www.ncbi.nlm.nih.gov/pubmed/26878911
http://dx.doi.org/10.1038/srep21133

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