Mutation of epigenetic regulators TET2 and MLL3 in patients with HTLV-I-induced acute adult T-cell leukemia

BACKGROUND: Epigenetic regulators play a critical role in the maintenance of specific chromatin domains in an active or repressed state. Disruption of epigenetic regulatory mechanisms is widespread in cancer cells and largely contributes to the transformation process through active repression of tum...

Descripción completa

Detalles Bibliográficos
Autores principales: Yeh, Chien-Hung, Bai, Xue Tao, Moles, Ramona, Ratner, Lee, Waldmann, Thomas A., Toshiki, Watanabe, Nicot, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754821/
https://www.ncbi.nlm.nih.gov/pubmed/26880370
http://dx.doi.org/10.1186/s12943-016-0500-z

Ejemplares similares

Ejemplares similares