(−)-Epigallocatechin-3-Gallate Enhances Hepatitis C Virus Double-Stranded RNA Intermediates-Triggered Innate Immune Responses in Hepatocytes

(−)-Epigallocatechin-3-gallate (EGCG), a major polyphenol component of green tea, has recently been identified as an inhibitor of hepatitis C virus (HCV) entry. Here, we examined whether EGCG can enhance hepatocyte-mediated intracellular innate immunity against HCV. HCV dsRNAs (Core, E1-P7, NS-3′NTR...

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Detalles Bibliográficos
Autores principales: Wang, Yizhong, Li, Jieliang, Wang, Xu, Peña, Juliet C., Li, Kui, Zhang, Ting, Ho, Wenzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754899/
https://www.ncbi.nlm.nih.gov/pubmed/26879672
http://dx.doi.org/10.1038/srep21595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754899/
https://www.ncbi.nlm.nih.gov/pubmed/26879672
http://dx.doi.org/10.1038/srep21595

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