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Increased availability of NADH in metabolically engineered baker’s yeast improves transaminase-oxidoreductase coupled asymmetric whole-cell bioconversion

BACKGROUND: Saccharomyces cerevisiae can be engineered to perform a multitude of different chemical reactions that are not programmed in its original genetic code. It has a large potential to function as whole-cell biocatalyst for one-pot multistep synthesis of various organic molecules, and it may...

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Detalles Bibliográficos
Autores principales: Knudsen, Jan Dines, Hägglöf, Cecilia, Weber, Nora, Carlquist, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754910/
https://www.ncbi.nlm.nih.gov/pubmed/26879378
http://dx.doi.org/10.1186/s12934-016-0430-x