Cargando…
RAB18, a protein associated with Warburg Micro syndrome, controls neuronal migration in the developing cerebral cortex
BACKGROUND: Loss of function mutations in RAB18, has been identified in patients with the human neurological and developmental disorder Warburg Micro syndrome. However, the function of RAB18 in brain remains unknown. RESULTS: In this study, we report that RAB18 is a critical regulator of neuronal mi...
Autores principales: | Wu, Qinwei, Sun, Xiaqin, Yue, Weihua, Lu, Tianlan, Ruan, Yanyan, Chen, Tianda, Zhang, Dai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754921/ https://www.ncbi.nlm.nih.gov/pubmed/26879639 http://dx.doi.org/10.1186/s13041-016-0198-2 |
Ejemplares similares
-
Tcf4 Controls Neuronal Migration of the Cerebral Cortex through Regulation of Bmp7
por: Chen, Tianda, et al.
Publicado: (2016) -
Ezh2 is involved in radial neuronal migration through regulating Reelin expression in cerebral cortex
por: Zhao, Linnan, et al.
Publicado: (2015) -
Warburg Micro syndrome is caused by RAB18 deficiency or dysregulation
por: Handley, Mark T., et al.
Publicado: (2015) -
A novel mouse model of Warburg Micro syndrome reveals roles for RAB18 in eye development and organisation of the neuronal cytoskeleton
por: Carpanini, Sarah M., et al.
Publicado: (2014) -
Two novel homozygous RAB3GAP1 mutations cause Warburg micro syndrome
por: Imagawa, Eri, et al.
Publicado: (2015)