Knockout of BRD7 results in impaired spermatogenesis and male infertility

BRD7 was originally identified as a novel bromodomain gene and a potential transcriptional factor. BRD7 was found to be extensively expressed in multiple mouse tissues but was highly expressed in the testis. Furthermore, BRD7 was located in germ cells during multiple stages of spermatogenesis, rangi...

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Detalles Bibliográficos
Autores principales: Wang, Heran, Zhao, Ran, Guo, Chi, Jiang, Shihe, Yang, Jing, Xu, Yang, Liu, Yukun, Fan, Liqing, Xiong, Wei, Ma, Jian, Peng, Shuping, Zeng, Zhaoyang, Zhou, Yanhong, Li, Xiayu, Li, Zheng, Li, Xiaoling, Schmitt, David C., Tan, Ming, Li, Guiyuan, Zhou, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754950/
https://www.ncbi.nlm.nih.gov/pubmed/26878912
http://dx.doi.org/10.1038/srep21776

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