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Comparison of Exome and Genome Sequencing Technologies for the Complete Capture of Protein‐Coding Regions

For next‐generation sequencing technologies, sufficient base‐pair coverage is the foremost requirement for the reliable detection of genomic variants. We investigated whether whole‐genome sequencing (WGS) platforms offer improved coverage of coding regions compared with whole‐exome sequencing (WES)...

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Detalles Bibliográficos
Autores principales:	Lelieveld, Stefan H., Spielmann, Malte, Mundlos, Stefan, Veltman, Joris A., Gilissen, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Methods
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755152/ https://www.ncbi.nlm.nih.gov/pubmed/25973577 http://dx.doi.org/10.1002/humu.22813

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