ASSOCIATION AMONG HISTOLOGICAL FINDINGS SUGGESTIVE OF PAPILLOMA VIRUS ON HEMORRHOIDECTOMY SPECIMENS

BACKGROUND: Many researchers studied human Papillomavirus infection in the anal area supposing it represents a risk factor for precursor lesions of anal cancer. AIM: To study the association between histological findings suggestive of injury by the virus in hemorrhoidectomy specimens. METHOD: Preval...

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Detalles Bibliográficos
Autores principales: da SILVA, Soraya Souto, NAKAJIMA, Gerson Suguiyama, GUIMARÃES, Ricardo Alexandre, MOURÃO, Flávia da Costa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Cirurgia Digestiva 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755177/
https://www.ncbi.nlm.nih.gov/pubmed/26734795
http://dx.doi.org/10.1590/S0102-6720201500040009
Descripción
Sumario:BACKGROUND: Many researchers studied human Papillomavirus infection in the anal area supposing it represents a risk factor for precursor lesions of anal cancer. AIM: To study the association between histological findings suggestive of injury by the virus in hemorrhoidectomy specimens. METHOD: Prevalence study was carried out based on histopathological analysis of hemorrhoidectomy specimens to find viral cytopathic effects. These findings were compared with anal condyloma acuminata that had no relationship with hemorrhoidectomy for microscopic comparison. RESULTS: Of the 91 hemorroidectomies analyzed, eight had findings suggestive of viral cytopathic effects, with the presence of irregular acanthosis in 63%, koilocytes in 50% and other indirect viral cytopathic effects, such as hyperkeratosis (38%), parakeratosis (25% ) and papillomatosis (13%). CONCLUSION: This study was unable to conclude that there is an association between these two pathologic entities.

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