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Stable long‐term cultures of self‐renewing B cells and their applications

Monoclonal antibodies are essential therapeutics and diagnostics in a large number of diseases. Moreover, they are essential tools in all sectors of life sciences. Although the great majority of monoclonal antibodies currently in use are of mouse origin, the use of human B cells to generate monoclon...

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Detalles Bibliográficos
Autores principales: Kwakkenbos, Mark J., van Helden, Pauline M., Beaumont, Tim, Spits, Hergen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755196/
https://www.ncbi.nlm.nih.gov/pubmed/26864105
http://dx.doi.org/10.1111/imr.12395