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Canonical wnt signaling is required for commissural axon guidance

Morphogens have been identified as guidance cues for postcrossing commissural axons in the spinal cord. Shh has a dual effect on postcrossing commissural axons: a direct repellent effect mediated by Hhip as a receptor, and an indirect effect by shaping a Wnt activity gradient. Wnts were shown to be...

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Detalles Bibliográficos
Autores principales: Avilés, Evelyn C., Stoeckli, Esther T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755210/
https://www.ncbi.nlm.nih.gov/pubmed/26014644
http://dx.doi.org/10.1002/dneu.22307