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iBodies: Modular Synthetic Antibody Mimetics Based on Hydrophilic Polymers Decorated with Functional Moieties
Antibodies are indispensable tools for biomedicine and anticancer therapy. Nevertheless, their use is compromised by high production costs, limited stability, and difficulty of chemical modification. The design and preparation of synthetic polymer conjugates capable of replacing antibodies in biomed...
Autores principales: | Šácha, Pavel, Knedlík, Tomáš, Schimer, Jiří, Tykvart, Jan, Parolek, Jan, Navrátil, Václav, Dvořáková, Petra, Sedlák, František, Ulbrich, Karel, Strohalm, Jiří, Majer, Pavel, Šubr, Vladimír, Konvalinka, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755222/ https://www.ncbi.nlm.nih.gov/pubmed/26749427 http://dx.doi.org/10.1002/anie.201508642 |
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