The amygdalo-nigrostriatal network is critical for an optimal temporal performance

The amygdalo-nigrostriatal (ANS) network plays an essential role in enhanced attention to significant events. Interval timing requires attention to temporal cues. We assessed rats having a disconnected ANS network, due to contralateral lesions of the medial central nucleus of the amygdala (CEm) and...

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Autores principales: Es-seddiqi, Mouna, El Massioui, Nicole, Samson, Nathalie, Brown, Bruce L., Doyère, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755265/
https://www.ncbi.nlm.nih.gov/pubmed/26884227
http://dx.doi.org/10.1101/lm.041152.115
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author Es-seddiqi, Mouna
El Massioui, Nicole
Samson, Nathalie
Brown, Bruce L.
Doyère, Valérie
author_facet Es-seddiqi, Mouna
El Massioui, Nicole
Samson, Nathalie
Brown, Bruce L.
Doyère, Valérie
author_sort Es-seddiqi, Mouna
collection PubMed
description The amygdalo-nigrostriatal (ANS) network plays an essential role in enhanced attention to significant events. Interval timing requires attention to temporal cues. We assessed rats having a disconnected ANS network, due to contralateral lesions of the medial central nucleus of the amygdala (CEm) and dopaminergic afferents to the lateral striatum, as compared to controls (sham and ipsilateral lesions of CEm and dopaminergic afferents to LS) in a temporal bisection task. ANS disconnection induced poorer temporal precision and increased response latencies to a short duration. The present results reveal a role of the ANS network in temporal processing.
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spelling pubmed-47552652017-03-01 The amygdalo-nigrostriatal network is critical for an optimal temporal performance Es-seddiqi, Mouna El Massioui, Nicole Samson, Nathalie Brown, Bruce L. Doyère, Valérie Learn Mem Brief Communication The amygdalo-nigrostriatal (ANS) network plays an essential role in enhanced attention to significant events. Interval timing requires attention to temporal cues. We assessed rats having a disconnected ANS network, due to contralateral lesions of the medial central nucleus of the amygdala (CEm) and dopaminergic afferents to the lateral striatum, as compared to controls (sham and ipsilateral lesions of CEm and dopaminergic afferents to LS) in a temporal bisection task. ANS disconnection induced poorer temporal precision and increased response latencies to a short duration. The present results reveal a role of the ANS network in temporal processing. Cold Spring Harbor Laboratory Press 2016-03 /pmc/articles/PMC4755265/ /pubmed/26884227 http://dx.doi.org/10.1101/lm.041152.115 Text en © 2016 Es-seddiqi et al.; Published by Cold Spring Harbor Laboratory Press http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first 12 months after the full-issue publication date (see http://learnmem.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Brief Communication
Es-seddiqi, Mouna
El Massioui, Nicole
Samson, Nathalie
Brown, Bruce L.
Doyère, Valérie
The amygdalo-nigrostriatal network is critical for an optimal temporal performance
title The amygdalo-nigrostriatal network is critical for an optimal temporal performance
title_full The amygdalo-nigrostriatal network is critical for an optimal temporal performance
title_fullStr The amygdalo-nigrostriatal network is critical for an optimal temporal performance
title_full_unstemmed The amygdalo-nigrostriatal network is critical for an optimal temporal performance
title_short The amygdalo-nigrostriatal network is critical for an optimal temporal performance
title_sort amygdalo-nigrostriatal network is critical for an optimal temporal performance
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755265/
https://www.ncbi.nlm.nih.gov/pubmed/26884227
http://dx.doi.org/10.1101/lm.041152.115
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