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Structural Mechanisms of Hexameric Helicase Loading, Assembly, and Unwinding
Hexameric helicases control both the initiation and the elongation phase of DNA replication. The toroidal structure of these enzymes provides an inherent challenge in the opening and loading onto DNA at origins, as well as the conformational changes required to exclude one strand from the central ch...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000Research
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755419/ https://www.ncbi.nlm.nih.gov/pubmed/26918187 http://dx.doi.org/10.12688/f1000research.7509.1 |