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Higher expression levels of the HOXA9 gene, closely associated with MLL-PTD and EZH2 mutations, predict inferior outcome in acute myeloid leukemia

BACKGROUND: Although the biological insight of acute myeloid leukemia (AML) has increased in the past few years, the discovery of novel discriminative biomarkers remains of utmost value for improving outcome predictions. Systematical studies concerning the clinical implications and genetic correlati...

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Detalles Bibliográficos
Autores principales: Gao, Li, Sun, Junzhong, Liu, Fang, Zhang, Hui, Ma, Yigai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755436/
https://www.ncbi.nlm.nih.gov/pubmed/26929642
http://dx.doi.org/10.2147/OTT.S95279