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Toward a general physiologically-based pharmacokinetic model for intravenously injected nanoparticles

To assess the potential toxicity of nanoparticles (NPs), information concerning their uptake and disposition (biokinetics) is essential. Experience with industrial chemicals and pharmaceutical drugs reveals that biokinetics can be described and predicted accurately by physiologically-based pharmacok...

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Detalles Bibliográficos
Autores principales: Carlander, Ulrika, Li, Dingsheng, Jolliet, Olivier, Emond, Claude, Johanson, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755468/
https://www.ncbi.nlm.nih.gov/pubmed/26929620
http://dx.doi.org/10.2147/IJN.S94370