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Toward a general physiologically-based pharmacokinetic model for intravenously injected nanoparticles
To assess the potential toxicity of nanoparticles (NPs), information concerning their uptake and disposition (biokinetics) is essential. Experience with industrial chemicals and pharmaceutical drugs reveals that biokinetics can be described and predicted accurately by physiologically-based pharmacok...
Autores principales: | Carlander, Ulrika, Li, Dingsheng, Jolliet, Olivier, Emond, Claude, Johanson, Gunnar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755468/ https://www.ncbi.nlm.nih.gov/pubmed/26929620 http://dx.doi.org/10.2147/IJN.S94370 |
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