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Up-Regulation of ENO1 by HIF-1α in Retinal Pigment Epithelial Cells after Hypoxic Challenge Is Not Involved in the Regulation of VEGF Secretion

PURPOSE: Alpha-enolase (ENO1), a major glycolytic enzyme, is reported to be over-expressed in various cancer tissues. It has been demonstrated to be regulated by the Hypoxia-inducible factor 1-α (HIF-1α), a crucial transcriptional factor implicated in tumor progression and cancer angiogenesis. Choro...

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Detalles Bibliográficos
Autores principales:	Zheng, Feihui, Jang, Wai-Chi, Fung, Frederic K. C., Lo, Amy C. Y., Wong, Ian Y. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755565/ https://www.ncbi.nlm.nih.gov/pubmed/26882120 http://dx.doi.org/10.1371/journal.pone.0147961

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