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Impacts on Sirtuin Function and Bioavailability of the Dietary Bioactive Compound Dihydrocoumarin

The plant secondary metabolite and common food additive dihydrocoumarin (DHC) is an inhibitor of the Sirtuin family of NAD(+)-dependent deacetylases. Sirtuins are key regulators of epigenetic processes that maintain silent chromatin in yeast and have been linked to gene expression, metabolism, apopt...

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Detalles Bibliográficos
Autores principales:	Jacobi, Jennifer L., Yang, Bo, Li, Xu, Menze, Anna K., Laurentz, Sara M., Janle, Elsa M., Ferruzzi, Mario G., McCabe, George P., Chapple, Clint, Kirchmaier, Ann L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755582/ https://www.ncbi.nlm.nih.gov/pubmed/26882112 http://dx.doi.org/10.1371/journal.pone.0149207

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