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Release of Matrix Metalloproteinases-2 and 9 by S-Nitrosylated Caveolin-1 Contributes to Degradation of Extracellular Matrix in tPA-Treated Hypoxic Endothelial Cells

Intracranial hemorrhage remains the most feared complication in tissue plasminogen activator (tPA) thrombolysis for ischemic stroke. However, the underlying molecular mechanisms are still poorly elucidated. In this study, we reported an important role of caveolin-1 (Cav-1) s-nitrosylation in matrix...

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Detalles Bibliográficos
Autores principales:	Song, Haoming, Cheng, Youjun, Bi, Gang, Zhu, Yihui, Jun, Wei, Ma, Wenlin, Wu, Huimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755609/ https://www.ncbi.nlm.nih.gov/pubmed/26881424 http://dx.doi.org/10.1371/journal.pone.0149269

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