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Barriers and Challenges in Hyperemesis Gravidarum Research

Nausea and occasional vomiting in early pregnancy (NVP) are common. When vomiting is severe or protracted, it is referred to as hyperemesis gravidarum (HG). HG affects up to 3% of pregnancies and is characterized by weight loss, dehydration, electrolyte imbalance, and the need for hospital admission...

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Detalles Bibliográficos
Autores principales: Grooten, Iris J., Roseboom, Tessa J., Painter, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755698/
https://www.ncbi.nlm.nih.gov/pubmed/26917969
http://dx.doi.org/10.4137/NMI.S29523
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author Grooten, Iris J.
Roseboom, Tessa J.
Painter, Rebecca C.
author_facet Grooten, Iris J.
Roseboom, Tessa J.
Painter, Rebecca C.
author_sort Grooten, Iris J.
collection PubMed
description Nausea and occasional vomiting in early pregnancy (NVP) are common. When vomiting is severe or protracted, it is referred to as hyperemesis gravidarum (HG). HG affects up to 3% of pregnancies and is characterized by weight loss, dehydration, electrolyte imbalance, and the need for hospital admission. HG has significant consequences for maternal well-being, is associated with adverse birth outcomes, and leads to major health care costs. Treatment options are symptomatic, hampered by the lack of evidence-based options including studies on nutritional interventions. One of the reasons for this lack of evidence is the use of a broad range of definitions and outcome measures. An internationally accepted definition and the formulation of core outcomes would facilitate meta-analysis of trial results and implementation of evidence in guidelines to ultimately improve patient care.
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spelling pubmed-47556982016-02-25 Barriers and Challenges in Hyperemesis Gravidarum Research Grooten, Iris J. Roseboom, Tessa J. Painter, Rebecca C. Nutr Metab Insights Review Nausea and occasional vomiting in early pregnancy (NVP) are common. When vomiting is severe or protracted, it is referred to as hyperemesis gravidarum (HG). HG affects up to 3% of pregnancies and is characterized by weight loss, dehydration, electrolyte imbalance, and the need for hospital admission. HG has significant consequences for maternal well-being, is associated with adverse birth outcomes, and leads to major health care costs. Treatment options are symptomatic, hampered by the lack of evidence-based options including studies on nutritional interventions. One of the reasons for this lack of evidence is the use of a broad range of definitions and outcome measures. An internationally accepted definition and the formulation of core outcomes would facilitate meta-analysis of trial results and implementation of evidence in guidelines to ultimately improve patient care. Libertas Academica 2016-02-14 /pmc/articles/PMC4755698/ /pubmed/26917969 http://dx.doi.org/10.4137/NMI.S29523 Text en © 2015 the author(s), publisher and licensee Libertas Academica Ltd. This is an open-access article distributed under the terms of the Creative Commons CC-BY-NC 3.0 License.
spellingShingle Review
Grooten, Iris J.
Roseboom, Tessa J.
Painter, Rebecca C.
Barriers and Challenges in Hyperemesis Gravidarum Research
title Barriers and Challenges in Hyperemesis Gravidarum Research
title_full Barriers and Challenges in Hyperemesis Gravidarum Research
title_fullStr Barriers and Challenges in Hyperemesis Gravidarum Research
title_full_unstemmed Barriers and Challenges in Hyperemesis Gravidarum Research
title_short Barriers and Challenges in Hyperemesis Gravidarum Research
title_sort barriers and challenges in hyperemesis gravidarum research
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755698/
https://www.ncbi.nlm.nih.gov/pubmed/26917969
http://dx.doi.org/10.4137/NMI.S29523
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