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The splicing regulator PTBP1 controls the activity of the transcription factor Pbx1 during neuronal differentiation

The RNA-binding proteins PTBP1 and PTBP2 control programs of alternative splicing during neuronal development. PTBP2 was found to maintain embryonic splicing patterns of many synaptic and cytoskeletal proteins during differentiation of neuronal progenitor cells (NPCs) into early neurons. However, th...

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Detalles Bibliográficos
Autores principales: Linares, Anthony J, Lin, Chia-Ho, Damianov, Andrey, Adams, Katrina L, Novitch, Bennett G, Black, Douglas L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755740/
https://www.ncbi.nlm.nih.gov/pubmed/26705333
http://dx.doi.org/10.7554/eLife.09268