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Bidirectional interactions between indomethacin and the murine intestinal microbiota
The vertebrate gut microbiota have been implicated in the metabolism of xenobiotic compounds, motivating studies of microbe-driven metabolism of clinically important drugs. Here, we studied interactions between the microbiota and indomethacin, a nonsteroidal anti-inflammatory drug (NSAID) that inhib...
Autores principales: | Liang, Xue, Bittinger, Kyle, Li, Xuanwen, Abernethy, Darrell R, Bushman, Frederic D, FitzGerald, Garret A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755745/ https://www.ncbi.nlm.nih.gov/pubmed/26701907 http://dx.doi.org/10.7554/eLife.08973 |
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